Description
What is P21-adamantane?
P21-adamantane is a modified neurotrophin-mimetic peptide derived from the CNTF (ciliary neurotrophic factor) sequence, with an adamantane moiety attached to enhance blood-brain barrier penetration and receptor engagement. Activates STAT3/JAK signalling and BDNF expression. Studied for hippocampal neurogenesis, cognitive enhancement, and neuroprotection models, with the adamantane modification providing superior CNS bioavailability compared to unmodified P21. Research use only.
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