MGF 2mg | 10-Vial Kit | Mechano Growth Factor | Muscle Satellite Cell Research

$80.00

MGF 2mg | 20-Vial Kit — IGF-1 Ec splice variant (mechano growth factor) — local tissue isoform of IGF-1 activated by mechanical loading, studied for satellite cell activation and muscle repair independent of systemic IGF-1. ≥99% HPLC purity, MS confirmed, Janoshik COA. Research use only.

Description

What is MGF??

MGF (Mechano Growth Factor) is a splice variant of IGF-1 (the Ec isoform in humans, CAS 87081-35-4) produced locally in muscle tissue in response to mechanical loading or damage. The unique E-domain peptide (24 aa) of MGF activates satellite cell proliferation independently of the IGF-1 receptor — acting through a distinct receptor population to expand the myoblast pool before differentiation. After local depletion (~minutes), circulating systemic IGF-1 drives differentiation and protein synthesis. PEGylated MGF extends this half-life significantly for sustained research models.

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