Description
What is Tesamorelin??
Tesamorelin (CAS 218949-48-9) is a synthetic analogue of endogenous growth hormone-releasing hormone (GHRH) comprising the full 44-amino acid GHRH sequence conjugated to a trans-3-hexenoic acid moiety at the N-terminus — conferring improved stability against DPP-IV degradation and enhanced GHRHr binding. Molecular formula C₂₂₁H₃₆₆N₆₈O₇₀S, MW ~5135 Da. FDA-approved as Egrifta® for HIV-associated lipodystrophy, Tesamorelin stimulates pulsatile GH release, which subsequently elevates IGF-1 and drives selective visceral fat reduction — making it the premier GHRH analog for adipose-GH axis research.
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