Cardiogen (Ala-Glu-Asp-Arg, AEDR) is a synthetic tetrapeptide bioregulator developed by Prof. Vladimir Khavinson\u2019s team at the St. Petersburg Institute of Bioregulation and Gerontology. It belongs to the Cytogen family of synthetic Khavinson peptides \u2013 precise copies of the active site sequences found in cardiac tissue extracts. Cardiogen is investigated for its tissue-specific ability to penetrate to the cell nucleus and interact with DNA promoter regions in cardiomyocytes and cardiac fibroblasts \u2013 modulating gene expression programs linked to myocardial repair, protein synthesis restoration, fibrosis-associated ECM remodelling, and apoptosis regulation. Research applications span post-infarction remodelling, hypertension-induced cardiac hypertrophy, and fibroblast signalling relevant to both cardiac and prostate tissue microenvironments.<\/p>\n","protected":false},"excerpt":{"rendered":"
Cardiogen 20mg | 10-Vial Kit \u2014 AEDR Khavinson tetrapeptide bioregulator \u2014 cardiac-specific gene expression modulator studied for cardiomyocyte differentiation and age-related cardiac function research. \u226599% HPLC purity, MS confirmed, Janoshik COA. Research use only.<\/p>\n","protected":false},"featured_media":1060,"comment_status":"open","ping_status":"closed","template":"","meta":[],"iconvert-abtest-template":[],"product_brand":[],"product_cat":[27],"product_tag":[],"class_list":["post-1059","product","type-product","status-publish","has-post-thumbnail","product_cat-peptides","first","instock","shipping-taxable","purchasable","product-type-simple"],"yoast_head":"\n