1239264-98-2<\/a>) is a small peptidomimetic derived from angiotensin IV (Ang IV) that potentiates hepatocyte growth factor (HGF) signalling at the MET receptor. Molecular formula C\u2082\u2084H\u2083\u2089N\u2083O\u2084, MW 437.58 g\/mol. Unlike classical nootropics, Dihexa operates by stabilising HGF\u2013MET complexes, driving de novo synaptogenesis \u2014 the formation of new dendritic spines and synaptic connections \u2014 rather than simply modulating existing neurotransmitter systems. In preclinical studies it outperformed BDNF in spine density and was estimated to be 10\u2077-fold more potent than BDNF at synaptogenesis. It is highly lipophilic and CNS-penetrant, active via sc, ip, and transdermal routes.<\/p>\n","protected":false},"excerpt":{"rendered":"Dihexa 5mg | 10-Vial Kit \u2014 HGF\/MET agonist heptapeptide (PNB-0408) \u2014 activates hepatocyte growth factor receptor to drive hippocampal synaptogenesis and dendritic spine density; studied for cognitive enhancement and memory improvement. \u226599% HPLC purity, MS confirmed, Janoshik COA. Research use only.<\/p>\n","protected":false},"featured_media":1172,"comment_status":"open","ping_status":"closed","template":"","meta":[],"iconvert-abtest-template":[],"product_brand":[],"product_cat":[27],"product_tag":[],"class_list":["post-1107","product","type-product","status-publish","has-post-thumbnail","product_cat-peptides","first","instock","shipping-taxable","purchasable","product-type-simple"],"yoast_head":"\n
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