Description
What is Tamoxifen?
Tamoxifen is a first-generation triphenylethylene SERM — ER antagonist in breast tissue, partial ER agonist in bone/liver/uterus. Metabolised to endoxifen (CYP2D6) — the primary active metabolite. Also the most widely used inducer for tamoxifen-inducible CreERT2/loxP conditional knockout mouse models. CAS 10540-29-1.








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