Follistatin-344 1mg | 10-Vial Kit | FST-344 | Myostatin & Activin Inhibitor Research

Description

What is Follistatin??

Follistatin (FST-344, CAS 122956-17-2) is a single-chain glycoprotein (MW ~35 kDa for FST-344 isoform) belonging to the TGF-β superfamily binding protein class. It acts as a potent endogenous inhibitor of activins, myostatin (GDF-8), GDF-11, GDF-9, and BMPs by binding these ligands with high affinity and sequestering them from their receptors. FST-344 is the circulating, proteoglycan-binding–deficient isoform with broader systemic distribution than FST-288. It is a key research tool for studying muscle hypertrophy, fertility (FSH/activin axis), bone formation, and TGF-β pathway biology.