Description
What is KPV?
KPV (Alpha-MSH(11-13) — Anti-inflammatory tripeptide (Lys-Pro-Val)) is a 3-amino acid C-terminal alpha-MSH fragment. C-terminal tripeptide of alpha-MSH (Lys-Pro-Val) retaining anti-inflammatory activity via MC1R modulation. Inhibits NF-κB nuclear translocation, reduces IL-6, IL-8, and TNF-α production, and shows particular efficacy in intestinal epithelial and GI inflammation models.
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