Description
What is EPO (Erythropoietin)??
Erythropoietin (EPO, CAS 11096-26-7) is a 30.4 kDa glycoprotein hormone produced primarily by renal peritubular cells in response to hypoxia. Recombinant human EPO (rhEPO) binds the homodimeric EPO receptor (EPOR) on erythroid progenitor cells, activating JAK2/STAT5, PI3K/Akt, and MAPK signalling pathways — promoting red blood cell proliferation, differentiation, and survival. Beyond erythropoiesis, EPO research has expanded into neuroprotection, cardioprotection, and tissue ischaemia models through EPOR expression in non-haematopoietic tissues.






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