Description
Buy P21-Adamantane 10mg Online
Searching for “buy P21-adamantane 10mg online,” “P21 adamantane peptide,” “P021 adamantane,” “P21-adamantane research,” or “adamantylated CNTF peptide” reflects interest in this specialized synthetic neurogenic research compound. This guide explains what P21-adamantane is, clarifies the 10mg research format, covers legal status, quality factors, costs, and important safety considerations.
Critical disclaimer: P21-adamantane (also known as P21 or P021) is sold strictly for laboratory research and development purposes only. It is not approved by the FDA or other major regulatory agencies as a drug, dietary supplement, or therapeutic agent for human use. Research-grade material is not intended for human or animal consumption, injection, or any therapeutic application. There are no completed human clinical trials establishing safety or efficacy. This article is for informational and educational purposes only and does not constitute medical advice. Always consult qualified professionals and comply with applicable laws when handling research chemicals.
What Is P21-Adamantane?
P21-adamantane is a synthetic adamantane-modified tetrapeptide designed as a mimetic of a biologically active fragment of ciliary neurotrophic factor (CNTF). CNTF is a neurotrophic protein that supports neuronal survival and neurogenesis, but the full-length protein is large and does not readily cross the blood-brain barrier when given peripherally.
Researchers created this compound by isolating a short active sequence from CNTF and attaching an adamantane group. The adamantane modification improves metabolic stability and enhances the ability of the small peptide to reach the brain. Common molecular details listed for research material include:
- Sequence: Ac-Asp-Gly-Gly-Leu with C-terminal adamantane modification (often written Ac-DGGL(A)G-NH₂ or similar variants)
- Molecular weight: approximately 578–579 g/mol
- CAS number: 1246751-68-7
- Form: White to off-white lyophilized powder
In preclinical studies, the adamantane-modified peptide has been investigated for effects on BDNF signaling, hippocampal neurogenesis, and related pathways in animal models of aging and neurodegeneration. The evidence base remains limited to non-human research.
The 10mg Research Vial Format
The 10mg lyophilized vial is the standard size offered by most research peptide suppliers for P21-adamantane. The powder requires reconstitution with bacteriostatic water or another suitable solvent before laboratory use.
Reputable suppliers typically emphasize:
- Purity of ≥98–99% verified by HPLC (often with mass spectrometry confirmation)
- Third-party Certificates of Analysis (COA)
- Storage guidance (usually cool, dry conditions or –20°C for long-term stability of the sealed vial)
The 10mg quantity is practical for multi-dose experimental protocols or laboratories needing moderate amounts of material.
Legal and Regulatory Status
P21-adamantane is not FDA-approved for any medical indication. It is marketed and sold exclusively as a research chemical labeled “for research use only” or “not for human consumption.”
It has no established pathway for compounding as a prescription drug in major Western regulatory systems, and there are no approved pharmaceutical products containing this compound. Purchasing research-labeled material for personal human use falls outside regulated channels and carries quality, purity, sterility, and legal risks.
How Researchers Source P21-Adamantane 10mg Online
When evaluating research suppliers, prioritize:
- Independent third-party testing with accessible, lot-specific COAs
- Clear research-only disclaimers on product pages and labeling
- Transparent information on sequence, adamantane modification, molecular weight, purity, and handling
- Secure payment and shipping practices
Avoid sources that make therapeutic or human-use claims or lack verifiable testing documentation.
Cost of P21-Adamantane 10mg
Research-grade 10mg vials commonly range from approximately $90–$150+ depending on the supplier, claimed purity, testing documentation, and bulk discounts. Prices vary and should be verified directly with current vendors. Multi-vial purchases often reduce the per-vial cost.
Research Context, Handling, and Quality Notes
Preclinical research (primarily rodent models) has explored the adamantane-modified peptide in the context of hippocampal neurogenesis, BDNF upregulation, reduction of certain tau-related pathology markers, and cognitive performance in aging or Alzheimer’s-model animals. These findings remain limited to non-human studies; human clinical data are absent.
Laboratory handling best practices include:
- Reconstituting under conditions appropriate for the experimental design
- Following supplier storage recommendations for lyophilized and reconstituted material
- Using proper sterile technique and personal protective equipment
- Maintaining accurate records of lot numbers and COAs
As with all research chemicals, sterility, accurate measurement, and contamination control are essential for reproducible results.
Conclusion and Recommendations
P21-adamantane 10mg is a research-grade synthetic CNTF-derived peptide featuring an adamantane modification for enhanced stability and brain penetrance. It is available from specialized research suppliers in lyophilized 10mg vials labeled strictly for laboratory use only.
If your purpose is legitimate scientific investigation, select suppliers that provide independent third-party COAs and clear documentation of the adamantane-modified structure. This compound is not an approved treatment, nootropic, or therapeutic agent, and human clinical evidence is lacking.
For any concerns related to cognitive function, neurological health, or related areas, consult a qualified healthcare provider and rely on evidence-based medical approaches. Research chemicals labeled for laboratory use only should remain in controlled research settings.
Review current supplier testing data, storage requirements, and applicable regulations carefully. Prioritizing scientific integrity, safety, and legal compliance is the most responsible approach when working with research peptides such as P21-adamantane.






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