Description
What is ARA-290?
ARA-290 (Cibinetide) is an 11-amino acid synthetic peptide derived from the helix B surface peptide (HBSP) of erythropoietin (EPO). Unlike EPO itself, ARA-290 selectively activates the innate repair receptor (IRR) — a heterodimeric complex of the EPO receptor and the beta common receptor (βcR) — without engaging the classical homodimeric EPO receptor responsible for erythropoiesis. This separation of tissue-protective signalling from haematopoietic activity makes ARA-290 a focused research tool for studying EPO’s non-erythroid cytoprotective and anti-inflammatory properties.








Reviews
There are no reviews yet.