MOTS-c 20mg | 10-Vial Kit | Mitochondrial Peptide | Metabolic & Longevity Research

Description

What is MOTS-c??

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c, CAS 1457483-14-9) is a 16-amino acid mitochondria-derived peptide encoded within the 12S rRNA gene of mitochondrial DNA. Molecular formula C₉₄H₁₄₆N₂₈O₂₄S₂, MW 2174.5 g/mol. MOTS-c translocates to the nucleus in response to metabolic stress, where it activates AMPK, modulates the FOXO pathway, and upregulates GLUT4 glucose transporter expression. It is a key research tool for studying mitochondrial-nuclear retrograde signalling, metabolic flexibility, insulin sensitivity, and cellular longevity pathways.