PNC-27 10mg | 10-Vial Kit | 100mg Total | Anticancer Peptide

Description

What is PNC-27 10mg?

PNC-27 is a 32-amino acid chimeric anticancer peptide containing a p53 HDM-2-binding domain fused to a membrane-destabilising penetratin sequence. It binds HDM-2 (human MDM-2) expressed on the plasma membrane of cancer cells — an expression pattern absent in normal cells — inducing selective membranolysis of tumour cells via a pore-forming mechanism. This selectivity makes PNC-27 a highly specific research tool for studying cancer cell membrane disruption and MDM-2-targeted therapy without affecting normal cell viability.