Description
What is VIP??
VIP (Vasoactive Intestinal Peptide, CAS 37221-79-7) is a 28-amino acid neuropeptide hormone (His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH₂) first isolated from porcine intestine. Molecular formula C₁₄₇H₂₃₇N₄₃O₄₃S, MW 3326.78 g/mol. VIP acts at VPAC1 and VPAC2 receptors (Gs/cAMP) broadly expressed in CNS, lung, gut, immune cells, and vasculature. It is a potent smooth muscle relaxant, bronchodilator, immunomodulator, and circadian pacemaker peptide (via VPAC2 in the SCN) — making it one of the most pleiotropic neuropeptides in research.
Reviews
There are no reviews yet.